Track variants, panels, and binding data across engineering campaigns — with sequence lineage and AI-built analysis.
Antibody and protein engineering campaigns generate sprawling variant panels, each with sequences, expression conditions, and binding measurements that have to stay connected to make any sense. When sequences live in a design tool, expression in a notebook, and SPR or ELISA data in a pile of exports, ranking variants becomes archaeology. Cypher keeps the whole campaign — design, expression, and characterization — connected, so the best binder is a query, not a reconstruction.
One connected platform for the work you do today and the data you generate tomorrow.
Register every construct, variant, and panel with annotated protein and DNA sequences. Each variant traces back to its parent and the mutation that produced it, across rounds of affinity maturation.
Track expression conditions, yields, and purification steps as structured LIMS records — so you know which constructs express well, not just which ones bind.
Describe the analysis — "fit SPR sensorgrams, report kon/koff/KD per variant, and rank the panel" — and Cypher builds a reusable widget your team runs on every new plate.
Track ML- and structure-guided designs — model, version, predicted vs. measured affinity — so you can close the loop on what your design approach actually delivers.
Run sequence-verification pipelines and link results back to the originating construct automatically, so verified clones are unambiguous.
Generate and annotate a variant library against a lead, registering each construct with lineage to the parent and the mutations introduced.
Capture expression conditions and yields as structured records; flag constructs that express poorly before they waste assay capacity.
Upload SPR/BLI/ELISA data and run a reusable analysis widget to compute affinities and rank the panel.
Promote top variants into the next round with lineage intact, and feed measured affinities back to the design model.